NAPLEX Practice Questions

Your patient is a 58-year-old male who presents with onset of severe substernal chest pain and shortness of breath. An ECG reveals an acute STEMI, and he is on his way to the cardiac catheterization suite for percutaneous coronary intervention.Which of the following drugs used in acute coronary syndromes treated with PCI must undergo oxidation by hepatic P450 enzymes to an active form? A.ClopidogrelB.TiclopidineC.EptifibatideD.AspirinE.Warfarin

A patient with multibacillary leprosy is on dapsone, clofazimine, and rifampin. Which of the following is true regarding the mechanism of action of the medications listed? A.Dapsone is bacteriostatic because of its inhibitory effects on dihydrofolate reductaseB.Dapsone is bacteriostatic because of its inhibitory effects on myeloperoxidaseC.Clofazimine is bactericidal by directly inhibiting bacterial DNA polymeraseD.Rifampin is bacteriostatic by inhibiting RNA synthesis by blocking DNA-dependent RNA polymeraseE.Rifampin is bactericidal by inhibiting RNA synthesis by blocking DNA-dependent RNA polymerase

Which of the following represents the major route of metabolism for acetaminophen? A.GlucuronidationB.SulfationC.Cytochrome P-450 oxidationD.Direct renal excretionE.Plasma breakdown

A 15-year-old presents with 6 days of nasal congestion with thin, clear rhinorrhea. She notes mild facial pain but has had no fevers. She feels her symptoms are improving.What is the most likely cause of her symptoms? A.Streptococcus pneumoniaeB.ViralC.Moraxella catarrhalisD.Haemophilus influenzaeE.Staphylococcus aureus